Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 19, 2025Open Access

Cellular and Molecular Approaches to Spinal Cord Repair: A Hypothetical Therapeutic Framework

View Full Paper
Ask AI
Bookmark
Share

Authors

ARAli H. RafatiFAFateme AziziSSSeyedeh Marziyeh Jabbari Shiadeh

Discussion

Loading...

Member takes

Overview

This review proposes targeted therapies that improve regeneration and reduce inflammation in spinal cord injury, suggesting integrated approaches.

Key Points

  • Proposed framework enhances spinal cord repair by integrating cellular and molecular therapies, aiming for better outcomes in regeneration and recovery.
  • Key elements include anti-inflammatory strategies and astrocyte reprogramming, emphasizing their role in supporting axonal guidance during recovery.
  • Review of pharmacological agents like BDNF and Rolipram demonstrates their potential to modulate neuroimmune responses in spinal cord repair.
  • Highlights the critical need for innovative, cell-specific therapies to effectively address challenges in treating spinal cord injury.

Cite This Study

Rafati et al. (2025) studied this question.

synapsesocial.com/papers/68af409acf1dd9ea359ec728https://doi.org/10.20944/preprints202508.1371.v1
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Advancements in Spinal Cord Injury Treatment: Integrating Drug Delivery, Biophysical Stimulation, Cell-Based Therapies, and Tissue Engineering Approaches2025 · 9 citations
  2. 2Current frontiers in spinal cord injury research: A narrative review2025 · 6 citations
  3. 3Precision Recovery After Spinal Cord Injury: Integrating CRISPR Technologies, AI-Driven Therapeutics, Single-Cell Omics, and System Neuroregeneration2025 · 19 citations
  4. 4Repairing spinal cord injuries: the most promising current 1 biomaterials 2 for scaffolding and drug delivery, and the need for upgrade2025
  5. 5Stem Cell Therapy for Spinal Cord Injury2025