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August 20, 2025Frontiers in MicrobiologyOpen Access

The gut microbiome in lung cancer: from pathogenesis to precision therapy

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Authors

MSMiao ShiLWLongfei WangWHWentao Hu

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Overview

Review highlights the impact of gut microbiome on immune responses in lung cancer, suggesting novel therapeutic approaches.

Key Points

  • Findings show significant links between gut dysbiosis and resistance to immune checkpoint inhibitors in lung cancer.
  • Key evidence indicates that specific microbial signatures can predict disease outcomes and therapy responses.
  • Review synthesizes knowledge on microbial interventions like probiotics and Fecal Microbiota Transplantation for lung cancer treatment.
  • Understanding the gut-lung axis may enable personalized strategies for lung cancer management and improved therapies.

Cite This Study

Shi et al. (2025) studied this question.

synapsesocial.com/papers/68af4093cf1dd9ea359ec4bahttps://doi.org/10.3389/fmicb.2025.1606684
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Also Consider

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  5. 5Role of gut microbiota in cancer modulation: molecular mechanisms and emerging therapeutic strategies2026 · 1 citations