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July 15, 2025International Journal Of Health Science

Chemometric Analysis of Phytochemical Content and Antioxidant Activity of Ethanol Extract 70% and Ethyl Acetate of Kersen Leaf (Muntingia calabura L.)

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Authors

AHAfif Putri HabibahESEndang SetyowatiEBEmma Jayanti Besan

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Overview

Analysis reveals significant antioxidant activity in ethyl acetate and ethanol extracts of kersen leaf, indicating higher flavonoids may enhance effects.

Key Points

  • Ethyl acetate extract showed the highest antioxidant activity with an IC₅₀ value of 34.45 μg/mL, indicating its potency.
  • Total flavonoid content was notably higher in the 70% ethanol extract at 3.374 mg EK/mL compared to 2.726 mg EK/mL in ethyl acetate.
  • The study utilized maceration and UV-Vis spectrophotometry to determine flavonoid and phenolic content in kersen leaf extracts.
  • Chemometric analysis using PCA highlighted the relationship between flavonoid content and antioxidant activity based on DPPH testing.

Cite This Study

Habibah et al. (2025) studied this question.

synapsesocial.com/papers/68af3e4fcf1dd9ea359ebc5ahttps://doi.org/10.55606/ijhs.v5i2.5583
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Also Consider

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  1. 1Analisis Fitokimia Daun Kersen (Mutingia calabura)2025
  2. 2Chemometric Analysis of Phytochemical Content and Antioxidant Activity of 70% Ethanol and Ethyl Acetate Extracts of Butterfly Pea Flowers2025 · 1 citations
  3. 3Antibacterial Activity of Kersen Leaf Extract (<i>Muntingia calabura</i> Linn.) Against <i>Salmonella typhi</i> and <i>Staphylococcus aureus</i> Using Bioautography Method2025
  4. 4Analysis of the Effect of Maceration and Soxhletation Extraction Methods on the Antioxidant Activity of Sungkai Leaf Ethanol Extract (Peronema canescens Jack)2025
  5. 5Metabolite profiling and antioxidant activity of peel extract from Citrus amblycarpa2025