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August 19, 2025F1000ResearchOpen Access

Hypoglycemic effect of the aqueous extract from Acalypha argomuelleri Briq. ' Sweet stick' leaves in Rattus rattus var. albinus

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Authors

JRJorge G. RamosBHBerta Loja HerreraNANéstor Manuel Rodríguez Alayo

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Overview

Randomized trial demonstrated blood glucose reduction in Rattus rattus after Acalypha argomuelleri extract administration, suggesting potential for diabetes management.

Key Points

  • The aqueous extract of Acalypha argomuelleri significantly reduced blood glucose levels in rats, demonstrating a promising hypoglycemic effect.
  • The 300 mg/kg dosage showed the most effectiveness, resulting in near-normal glucose levels at 90 minutes post-administration.
  • This research utilized a randomized, prospective design, comparing control and treatment groups receiving varying doses of the extract.
  • Findings highlight the potential of Acalypha argomuelleri as a natural alternative for blood glucose control, warranting further clinical investigation.

Cite This Study

Ramos et al. (2025) studied this question.

synapsesocial.com/papers/68af35e3cf1dd9ea359ea248https://doi.org/10.12688/f1000research.164673.1
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Also Consider

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  1. 1Hypoglycemic effect of the aqueous extract from Acalypha argomuelleri Briq. (Euphorbiaceae) 'Sweet stick' leaves in Rattus rattus var. albinus2025
  2. 2Hypoglycemic effect of the aqueous extract from Acalypha argomuelleri Briq. (Euphorbiaceae) 'Sweet stick' leaves in Rattus rattus var. albinus2025
  3. 3Anti-hyperglycaemic effect of aqueous extract from 2025
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  5. 5Antidiabetic Properties of Medicago sativa (Alfalfa) Aqueous Leaf Extract on Alloxan-induced Diabetes in Albino Rats2025