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October 12, 2025F1000ResearchOpen Access

Hypoglycemic effect of the aqueous extract from Acalypha argomuelleri Briq. (Euphorbiaceae) 'Sweet stick' leaves in Rattus rattus var. albinus

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Authors

JRJorge G. RamosBHBerta Loja HerreraNANéstor Manuel Rodríguez Alayo

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Overview

Randomized, prospective design reveals blood glucose reduction in Rattus rattus, suggesting A. argomuelleri may aid diabetes management.

Key Points

  • The 300 mg/kg dose of Acalypha argomuelleri extract significantly reduced blood glucose levels after 90 minutes.
  • Phytochemical analysis identified flavonoids and phenols, indicating potential mechanisms for glucose metabolism modulation.
  • Higher doses showed faster and more sustained reductions, highlighting the dose-dependent nature of the extract's hypoglycemic effect.
  • Further studies are necessary to evaluate the safety and efficacy of Acalypha argomuelleri in clinical settings.

Cite This Study

Ramos et al. (2025) studied this question.

synapsesocial.com/papers/68ebe3d6becc64ad52fdaf58https://doi.org/10.12688/f1000research.164673.3
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