Serum Allergen‐Specific Immunoglobulin E Response in Dogs With Moderate‐To‐Severe Leishmaniosis

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Analysis reveals high allergen-specific IgE levels in dogs with leishmaniosis, suggesting caution in interpreting serology tests.

Dogs with leishmaniosis show a significantly higher rate of allergen-specific IgE than healthy dogs, indicating an altered immune response.
In serum samples, median allergen-specific IgE concentrations were 7.1 U/mL in leishmaniotic dogs, compared to 1.4 U/mL in healthy ones.
The comparison included 47 dogs with leishmaniosis, alongside 30 atopic and 33 healthy dogs across multiple analyses.
These findings underscore the need for cautious interpretation of allergen tests in leishmaniosis-affected dogs.

Cabré et al. (2025) studied this question.

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