Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 19, 2025The American Surgeon

Research Progress on Neoadjuvant Immunotherapy in Esophageal Squamous Cell Carcinoma

View Full Paper
Ask AI
Bookmark
Share

Authors

WHWenyuan HongXLXuqiang LiaoCXChaoyang Xia

Discussion

Loading...

Member takes

Overview

Narrative review summarizes emerging neoadjuvant immunotherapy strategies in esophageal squamous cell carcinoma, highlighting clinical trial findings and ongoing challenges.

Key Points

  • Neoadjuvant immunotherapy shows promise for improving outcomes in esophageal squamous cell carcinoma, addressing limitations of traditional treatments.
  • Recent clinical trials indicate that combining chemotherapy with immune checkpoint inhibitors potentially enhances treatment efficacy.
  • This narrative review synthesizes findings from various studies on neoadjuvant immunotherapy approaches targeting resectable ESCC cases.
  • Challenges related to adverse effects and drug resistance in existing therapies highlight the need for ongoing research and innovative strategies.

Cite This Study

Hong et al. (2025) studied this question.

synapsesocial.com/papers/68af33e9cf1dd9ea359e9125https://doi.org/10.1177/00031348251367030
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Neoadjuvant immunochemotherapy versus neoadjuvant chemoradiotherapy versus neoadjuvant chemotherapy for resectable esophageal squamous cell carcinoma: a clinical retrospective study2025
  2. 2Efficacy of neoadjuvant chemoimmunotherapy in locally advanced resectable esophageal cancer2025
  3. 3Editorial: The role of adjuvant and neoadjuvant therapy in resectable esophageal cancer2025
  4. 4474. NEOADJUVANT CHEMOIMMUNOTHERAPY VERSUS CHEMOTHERAPY PLUS ESOPHAGECTOMY FOR ESOPHAGEAL SQUAMOUS CELL CARCINOMA: PRIMARY RESULT OF A RANDOMIZED CLINICAL TRIAL2025
  5. 5Analysis of the safety and efficacy of PD-1/PD-L1 inhibitors combined with chemotherapy in the treatment of locally advanced resectable esophageal squamous cell carcinoma: a systematic review and meta-analysis based on four randomized controlled trials2025