August 17, 2025Scientific ReportsOpen Access

Exploring the shared genetic basis between autism spectrum disorder and gastrointestinal disorders: a bioinformatic study

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Bioinformatic analysis reveals limited shared genetic mutations in autism, IBD, and celiac disease, suggesting further exploration is necessary.

Only 3 shared genetic mutations were identified between autism spectrum disorder and gastrointestinal disorders like IBD and celiac disease.
A total of 2367 variation disease associations were found for autism spectrum disorder, with additional counts for related GI diseases.
The methodology utilized bioinformatics tools from databases such as DisGeNET and Genome Wide Association Study.
Findings highlight the need for deeper investigations into the genetic links and implications for autism and GI disorders.

Malekpour et al. (2025) studied this question.

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Bioinformatic analysis reveals limited shared genetic mutations in autism, IBD, and celiac disease, suggesting further exploration is necessary.