Screening and Diagnosis of Depression: Correlation of Genomic Alterations With Functional Magnetic Resonance Imaging

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Observational analysis correlates genetic alterations with fMRI findings in major depressive disorder, indicating diagnostic advancements.

Preliminary findings indicate notable SNPs in the DAOA and TPH1 genes linked to major depressive disorder.
Research involved 400 participants, comparing genetic data and fMRI findings between depressed individuals and controls.
The study utilized next-generation sequencing and functional MRI to investigate the molecular basis of depression.
Integration of genetic markers with neuroimaging may enable precision diagnostics and tailored therapies for depression.

Singh et al. (2025) studied this question.

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Observational analysis correlates genetic alterations with fMRI findings in major depressive disorder, indicating diagnostic advancements.