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August 1, 2025The International Journal of NeuropsychopharmacologyOpen Access

Research on Transcranial Pulse Stimulation (Tps) in Major Depressive Disorder (Mdd)

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Authors

GKGeorg S. KranzHong Kong Polytechnic University

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Implication

Randomized, double-blind trials reveal TPS improves depressive symptoms in MDD, indicating its potential as a treatment.

Key Points

  • Transcranial pulse stimulation significantly reduces depressive symptoms, showing promising therapeutic potential.
  • In trials, TPS applied to the motor cortex observed improvements in motor performance assessed with the Nine-hole peg test.
  • Randomized, double-blind, sham-controlled trials targeted the dorsolateral prefrontal cortex to evaluate effectiveness in MDD.
  • TPS might shift treatment strategies for depression, emphasizing its relevance in psychiatric disorders beyond just MDD.

Cite This Study

Georg S. Kranz (2025) studied this question.

synapsesocial.com/papers/68af2ee5cf1dd9ea359e6831https://doi.org/10.1093/ijnp/pyaf052.383
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1272. EFFECTIVENESS OF TRANSCRANIAL PULSE STIMULATION FOR MAJOR DEPRESSION: PRELIMINARY EVIDENCE FOR CLINICAL RESPONSE AND NEUROIMAGING MECHANISMS2025
  2. 2Transcranial Pulse Stimulation (TPS) suitable add-on treatment of patients with psychiatric disorders?2025
  3. 3New therapeutic option for treatment-resistant depression using transcranial pulse stimulation: real-world data from a case series2025
  4. 4Neuronavigated Transcranial Pulse Stimulation (TPS) with shock waves as a novel tool of noninvasive brainstimulation (NIB) for a long-term treatment of Alzheimer’s disease2025
  5. 5Transcranial Pulse Stimulation in Alzheimer’s: Long-Term Feasibility and a Multifocal Treatment Approach2025 · 5 citations