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August 9, 2025UPI Journal of Pharmaceutical Medical and Health Sciences

Evaluation of Invivo Antidepressant and Invitro Antioxidant Activities of Ethanolic Extract of Calendula Officinalis

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Authors

MMMadhavi Kumari MRARamya Arimilli

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Overview

This study demonstrates antidepressant effects through forced swim and tail suspension tests, highlighting the extract's antioxidant potential.

Key Points

  • The extract significantly reduced immobility time in the forced swim test, indicating potential antidepressant effects.
  • In vitro antioxidant activities showed strong scavenging ability against DPPH free radicals, highlighting its therapeutic potential.
  • Assessment involved standard animal models like the forced swim test and laboratory assays for antioxidant evaluation.
  • The findings suggest that bioactive compounds may contribute to the pharmacological effects of calendula officinalis, warranting further research.

Cite This Study

M et al. (2025) studied this question.

synapsesocial.com/papers/68af2979cf1dd9ea359e3382https://doi.org/10.37022/jpmhs.v8i2.136
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Calendula (Calendula officinalis) Marigold as Medicinal Plant2023
  2. 2Phenolic Profile and Antioxidant Potential of Calendula Officinalis and Achillea Millefolium Eco-friendly Extracts: A Comparative Study2025
  3. 3Calendula Arvensis L. Extracts: GC-MS And HPLC-DAD Quantification Of The Main Phenolic Components And Their Pharmacological Potential2025
  4. 4Investigation of the effect of watery and alcoholic extract of Calendula officinalis on the growth of fungal agents isolated from skin infections caused by burns2023
  5. 5Phytochemical Screening and Anti-Ageing Potential of Herbal Extracts in A Topical Cream Formulation2025