August 10, 2025Plant Science TodayOpen Access

Exploring the therapeutic potential of leaf extract of Nephrolepis brownii (Desv.) Hovenkamp & Miyam.: An integrative study on antioxidant and anti-diabetic activities

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Discussion

Integrative study demonstrates antioxidant and anti-diabetic effects of N. brownii leaf extract, suggesting its therapeutic potential.

N. brownii leaf extract shows substantial antioxidant activity, achieving 70.0% inhibition at 1000 μg/mL in the DPPH radical scavenging assay.
The extract inhibits α-amylase and α-glucosidase in a concentration-dependent manner, with IC50 values of 67.70 μg/mL and 76.37 μg/mL respectively.
Comparison with acarbose reveals that while effective, N. brownii's anti-diabetic potency is slightly lower yet still significant.
These findings underscore the natural therapeutic potential of N. brownii, advocating for its use in future anti-diabetic research.

Geetha et al. (2025) studied this question.

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