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August 10, 2025The International Journal of Medical Science and Health Research

What is the effectiveness of structured lifestyle interventions (diet, exercise, sleep hygiene) in preventing relapse among adults with recurrent major depressive disorder ? : A Systematic Review

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Authors

RARatu Qurroh' AinMSMelsha SyarahhandiMSMelati Rosa Sitorus

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Overview

Systematic review shows that psychological interventions reduce relapse rates in adults with recurrent major depressive disorder, highlighting their effectiveness over dietary changes.

Key Points

  • Psychological interventions reduce relapse risk, achieving hazard ratios around 0.60 for efficacy.
  • Combined lifestyle and exercise programs are effective, with adherence playing a crucial role; one study showed 7.4% relapse versus 25.3% in controls.
  • Dietary interventions improve symptoms but do not consistently lower relapse rates, particularly when using Mediterranean diets.
  • The effectiveness varies significantly across non-pharmacological interventions, underlining the need for tailored approaches in MDD treatment.

Cite This Study

Ain et al. (2025) studied this question.

synapsesocial.com/papers/68af2974cf1dd9ea359e3001https://doi.org/10.70070/e9d77371
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Lifestyle Interventions for Depression: An Umbrella Review of Systematic Reviews and Meta-Analyses (Preprint)2025
  2. 2Does a lifestyle-based intervention improve sleep quality in individuals with major depressive disorder? A randomized controlled trial.2025
  3. 3Predictive Factors of Recurrence in Patients with Major Depressive Disorder2025
  4. 4Effectiveness of mHealth interventions targeting physical activity, sedentary behaviour, sleep or nutrition on emotional, behavioural and eating disorders in adolescents: a systematic review and meta-analysis2025 · 8 citations
  5. 5Relationship between lifestyle interventions and improvement in anxiety symptoms in primary care: a systematic review2025