Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 16, 2025

Influence of Nitric Oxide-Releasing Hyaluronic Acid Form on Immune Modulation.

View Full Paper
Ask AI
Bookmark
Share

Authors

SPSamantha L. PicciottiHEHeba El-AhmadMWMatthew F. Warchol

Discussion

Loading...

Member takes

Overview

Assessment of nitric oxide-releasing hyaluronic acid properties shows immunomodulatory effects on macrophages, indicating implications for chronic inflammation.

Key Points

  • Nitric oxide-releasing hyaluronic acid derivatives influence macrophage polarization, impacting immune regulation.
  • HA molecular weight plays a critical role in NO-release kinetics, affecting immunomodulatory activity.
  • Macrophages interact with HA derivatives, with performance varying based on HA modifications and structure.
  • Biocompatibility remains consistent across HA types, underscoring their potential in therapeutic applications.

Cite This Study

Picciotti et al. (2025) studied this question.

synapsesocial.com/papers/68a35140234c60ad5c20c9b6https://doi.org/10.1021/acs.biomac.5c00585
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hyaluronic Acid in Immune Response2025
  2. 2Hyaluronic acid impacts the inflammatory potential and pathogenicity of autoreactive Th17 cells 30392025
  3. 3Impact of intra-articular high-concentration hyaluronic acid administration on the innate immune response in experimental knee osteoarthritis2025
  4. 4Modelling the Detailed Conformational Effects of the Lactosylation of Hyaluronic Acid2024
  5. 5Hyaluronidases as Targets for the Treatment of Neurological Diseases2025 · 1 citations