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August 14, 2025Discover OncologyOpen Access

Metabolomics-based liquid biopsy reflects molecular alterations induced by meningioma

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Authors

GKGabriel A. KurokawaPFPedro Tadao Hamamoto FilhoAGAngélique Galvani

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Overview

Analysis identifies plasma metabolites as potential meningioma biomarkers, suggesting a simpler detection method.

Key Points

  • Three metabolites were identified as potential biomarkers for meningioma, supporting their role in diagnosis.
  • Hydroxymethyluracil showed a remarkable AUC of 0.93, indicating strong potential for differentiation from healthy controls.
  • This study utilized untargeted metabolomics and mass spectrometry methods to evaluate plasma samples from meningioma patients.
  • These findings highlight a new avenue for identifying tumor biomarkers in blood, improving patient monitoring.

Cite This Study

Kurokawa et al. (2025) studied this question.

synapsesocial.com/papers/68a34f4c234c60ad5c20b759https://doi.org/10.1007/s12672-025-03374-6
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Also Consider

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  1. 1Potential Causal Relationship Between Plasma and Cerebrospinal Fluid Metabolites and Meningioma: Two-Sample Mendelian Randomization Study2025
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  4. 4Identification of Malignant Progression of Gliomas through Metabolomics of Cerebrospinal Fluid and Serum2025
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