August 15, 2025Open Access

Role of NLRP3 Inflammasomes in Disorders of the Children’s Digestive System

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Discussion

This review evaluates NLRP3 inflammasomes' role in gastrointestinal and hepatic disorders among children, suggesting potential therapeutic values.

NLRP3 inflammasomes have a dual role in protecting and causing issues in digestive health.
Research highlights NLRP3's involvement in pediatric conditions like inflammatory bowel diseases and autism.
A comprehensive analysis of current literature on NLRP3 inflammasomes and disorders in children is presented.
Potential therapies targeting NLRP3 inflammasome may offer new treatment options for gastrointestinal disorders.

Safaa ELMeneza (2025) studied this question.

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This review evaluates NLRP3 inflammasomes' role in gastrointestinal and hepatic disorders among children, suggesting potential therapeutic values.