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August 10, 2025

Enhancing Cognitive Function and Well-being in Older Adults With Cognitive and Physical Decline: A Meta-analysis of Randomized Controlled Trials Examining Physical Activity Interventions.

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Authors

JCJing‐Yu ChangKCKuei‐Ru ChouYCYu‐Ling Chang

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Overview

Meta-analysis reveals physical activity interventions enhance cognitive function and well-being in older adults with frailty, suggesting individualized approaches in geriatric care.

Key Points

  • Physical activity interventions yield small-to-moderate improvements in cognitive function, with notable gains in global cognition.
  • The meta-analysis included 42 randomized controlled trials, encompassing 4740 older adults with cognitive or physical frailty.
  • Moderate effects on physical health-related quality of life and strong effects on psychological well-being were observed from these interventions.
  • Multicomponent and resistance-based exercise programs are effective in promoting both cognitive function and overall well-being in older adults.

Cite This Study

Chang et al. (2025) studied this question.

synapsesocial.com/papers/689e03d9d61984b91e13ca3ahttps://doi.org/10.1123/jpah.2025-0401
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effects of exercise interventions on physical function, cognitive function and quality of life of frail older adults in nursing homes: a systematic review and meta-analysis2025 · 5 citations
  2. 2Mind–body training outperforms other physical activities in reducing frailty and enhancing quality of life in older adults: a network meta-analysis2025 · 2 citations
  3. 3The effect of resistance training for older adults with cognitive frailty: a randomized controlled trial2025
  4. 4Effects of different physical activity interventions on executive function in older adults with dementia: a systematic review and network meta-analysis2025
  5. 5Effect of a wearable-sensor-assisted multicomponent exercise program on physical fitness, cognition and quality of life in frail older adults2025