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August 5, 2025

Effect of left bundle branch area pacing on cardiac remodeling and function: propensity score matching with right ventricular pacing

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Authors

SZShigeng ZhangZLZongbin LiJGJunfang Guo

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Overview

Propensity score matching shows improved cardiac remodeling with left bundle branch area pacing over right ventricular pacing in patients with AV block.

Key Points

  • Left bundle branch area pacing stabilizes cardiac function in patients with ejection fraction ≥50%.
  • Significant improvement in left ventricular ejection fraction observed in patients with ejection fraction <50% after LBBAP.
  • Propensity score matching yielded 41 pairs, ensuring comparable baseline characteristics for analysis.
  • LBBAP may reduce pacing-induced cardiomyopathy incidence compared to conventional right ventricular pacing.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/689a0f93e6551bb0af8d10a1https://doi.org/10.21203/rs.3.rs-6695039/v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical outcomes of left bundle branch area pacing versus right ventricular pacing in patients with preserved ejection fraction2026
  2. 2Left bundle branch area pacing vs right ventricular pacing for atrioventricular block: the MELOS RELOADED study2025 · 32 citations
  3. 3Two-year outcomes of left bundle branch area pacing versus traditional right ventricular pacing in middle-aged adults: a registry-based trial2025 · 23 citations
  4. 4Left Bundle Branch Area Pacing Improves Left Atrial Outcomes in Pacemaker-Dependent Patients: A Prospective Cohort Study Using Speckle Tracking and Three-Dimensional Echocardiography.2025 · 1 citations
  5. 5Beyond QRS Narrowing: left bundle branch area pacing enhances ventricular synchrony and myocardial work2026