August 4, 2025CellsOpen Access

Human-Induced Pluripotent Stem Cells (iPSCs) for Disease Modeling and Insulin Target Cell Regeneration in the Treatment of Insulin Resistance: A Review

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Review highlights iPSC applications in insulin resistance and diabetes modeling, suggesting potential therapeutic avenues.

Human-induced pluripotent stem cells are revolutionizing the study and treatment of insulin resistance in diabetes.
iPSC-derived insulin target cells can be used for disease modeling and regenerative therapies in type 1 and type 2 diabetes.
The review discusses differentiation strategies and growth factors for generating specialized cells from iPSCs.
Understanding insulin resistance mechanisms through iPSCs may lead to improved treatment options for diabetes patients.

Thiab et al. (2025) studied this question.

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