Stem cell therapy for diabetes: Advances, prospects, and challenges

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This review evaluates stem cell therapy efficacy for diabetes mellitus, suggesting future directions amid safety and ethical challenges.

Stem cell therapy shows potential for managing diabetes mellitus, particularly through induced pluripotent and mesenchymal stem cells.
Clinical trials reveal both promising efficacy and significant safety concerns regarding stem cell treatments for diabetes.
Recent innovations include pancreatic islet organoids and personalized medicine approaches to enhance treatment outcomes.
Challenges like immune rejection and ethical issues must be addressed for successful integration of stem cell therapies in diabetes care.

Zuo et al. (2025) studied this question.

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