Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 4, 2025Signal Transduction and Targeted TherapyOpen Access

Mitochondrial metabolism and cancer therapeutic innovation

View Full Paper
Ask AI
Bookmark
Share

Authors

HDHongxiang DuTXTianhan XuSYSihui Yu

Discussion

Loading...

Member takes

Overview

This review highlights mitochondrial dysfunction and metabolism in cancer, suggesting new therapeutic approaches.

Key Points

  • Mitochondrial dysfunction plays a critical role in cancer development and treatment resistance.
  • Cancer cells exploit altered metabolic pathways, including glycolysis and glutamine metabolism, to support growth.
  • Mitochondria influence immune responses within the tumor microenvironment, affecting cell survival and function.
  • Targeting mitochondrial metabolism is a promising therapeutic strategy, despite challenges from heterogeneity.

Cite This Study

Du et al. (2025) studied this question.

synapsesocial.com/papers/689a0c7be6551bb0af8d0827https://doi.org/10.1038/s41392-025-02311-x
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Dysregulation of Mitochondrial Function in Cancer Cells2025 · 20 citations
  2. 2Mitochondria and Tumorigenesis2025
  3. 3Molecular Mediators of Metabolic Reprogramming in Cancer: Mechanisms, Regulatory Networks, and Therapeutic Strategies2025
  4. 4Mitochondrial Metabolomics in Cancer: Mass Spectrometry-Based Approaches for Metabolic Rewiring Analysis and Therapeutic Discovery2025
  5. 5Mitochondrial Ca<sup>2+</sup> in Cancer Growth and Metabolism2025