August 2, 2025Open Access

Wolbachia introgression in Rio de Janeiro remains at sub-optimal levels 30 months after its crash: challenges in the sustainability of wMel interventions for dengue control

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Field study reveals suboptimal wMel frequencies in Aedes aegypti populations, indicating challenges in dengue vector management.

The persistence of the wMel strain is low in Rio de Janeiro, averaging only 9.87% across neighborhoods.
Routine insecticide rotation hindered the sustainability of wMel, which affects dengue control efforts.
Sampling across 12 neighborhoods highlighted significant variability in wMel frequencies, with only two areas above 15%.
These findings emphasize the difficulties in achieving long-term wMel establishment in urban Aedes aegypti populations.

Padilha et al. (2025) studied this question.

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