The impact of cardiac amyloidosis on patients with multiple myeloma: a systematic review and prognostic meta-analysis

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Cardiac AL amyloidosis notably affects survival outcomes for multiple myeloma patients with an increased mortality rate.
In patients with cardiac involvement, all-cause mortality at 12 months was nearly five times higher than those without.
Data from five studies involving 264 patients were analyzed to evaluate the impact of cardiac amyloidosis on prognosis.
These findings highlight the importance of assessing cardiac health in managing multiple myeloma for better patient outcomes.

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Systematic review shows cardiac amyloidosis significantly increases mortality in multiple myeloma patients, suggesting need for targeted care.

Stabile et al. (2025) studied this question.

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Systematic review shows cardiac amyloidosis significantly increases mortality in multiple myeloma patients, suggesting need for targeted care.