Control and treatment of obesity comorbidities by melatonin nutrological therapy: a systematic review

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Discussion

Systematic review confirms melatonin's role in regulating body weight and insulin sensitivity in obesity, suggesting potential therapeutic benefits.

MAIN FINDING: Melatonin significantly influences energy metabolism and is crucial in managing obesity comorbidities.
KEY EVIDENCE: 27 out of 30 studies showed melatonin improves insulin sensitivity and reduces obesity-related anthropometric indices.
APPROACH: The review adhered to PRISMA guidelines, analyzing various clinical studies including randomized controlled trials.
SIGNIFICANCE: Findings suggest melatonin management could be a valuable addition to obesity treatment strategies.

Góis et al. (2025) studied this question.

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Systematic review confirms melatonin's role in regulating body weight and insulin sensitivity in obesity, suggesting potential therapeutic benefits.