July 26, 2025Open Access

Non-invasive Stimulation of Contralateral Primary Motor Cortex Reduces the Amount of Skill Generalization to the Untrained Arm

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Stimulating contralateral primary motor cortex reduced skill generalization to the untrained arm.
Participants exposed to rTMS to cM1 showed less generalization compared to those stimulated in ipsilateral M1.
Low-frequency rTMS effectively assessed neuroplastic changes and corticospinal excitability in targeted motor areas.
Findings indicate cM1 mediates early transfer of learned motor skills to the untrained arm, impacting rehabilitation strategies.

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Experiment shows cM1 stimulation reduces skill generalization in right-handed individuals, suggesting a role in motor learning.

Yadav et al. (2025) studied this question.

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