Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 15, 2025Journal of Gastroenterology and HepatologyOpen Access

Helicobacter pylori Infection and Eradication in Relation to Gastroesophageal Reflux Disease

View Full Paper
Ask AI
Bookmark
Share

Authors

HWHejie WangYQYaxin QuLYLin Yuan

Discussion

Loading...

Member takes

Overview

Systematic review finds H. pylori infection reduces GERD risk, while eradication increases it, suggesting potential implications for treatment strategies.

Key Points

  • H. pylori infection is inversely associated with GERD risk, with a pooled odds ratio of 0.58.
  • Eradication of H. pylori increases GERD risk, reflected in a pooled odds ratio of 2.01.
  • Meta-analysis combined data from 24 studies, including cohort studies and randomized controlled trials.
  • Findings may influence clinical approaches to managing GERD and H. pylori treatment strategies.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/689a02bce6551bb0af8cc7c0https://doi.org/10.1111/jgh.70009
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evaluating Helicobacter pylori as a Risk Modifier for Barrett’s Esophagus in Gastroesophageal Reflux Disease: Insights From a Multicenter Electronic Health Record-Based Study2025
  2. 2The Controversies in the Relationship Between Helicobacter pylori Infection and Inflammatory Bowel Disease: Narrative Review2025 · 1 citations
  3. 3Association of Helicobacter pylori as an Extragastric Reservoir in the Oral Cavity with Oral Diseases in Patients with and Without Gastritis—A Systematic Review2025
  4. 4Effects of <i>Helicobacter pylori</i> Eradication on the Risk and Clinical Parameters of Metabolic Dysfunction‐Associated Steatotic Liver Disease: A Systematic Review and Meta‐Analysis2025
  5. 5Epidemiology of dyspepsia and esophagogastroduodenoscopic findings in the era of <i>Helicobacter pylori</i> eradication2025 · 2 citations