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September 5, 2025Journal of Clinical MedicineOpen Access

The Controversies in the Relationship Between Helicobacter pylori Infection and Inflammatory Bowel Disease: Narrative Review

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Authors

JVJonatan VukovićIJIvana Jukić

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Overview

This narrative review explores the association between helicobacter pylori and inflammatory bowel disease, highlighting infection prevalence and treatment implications.

Key Points

  • Significantly lower prevalence of helicobacter pylori infection is observed in inflammatory bowel disease patients compared to the general population.
  • Meta-analyses suggest helicobacter pylori may protect against inflammatory bowel disease, especially in crohn's disease patients.
  • Eradication therapy's impact on inflammatory bowel disease progression shows variability, with some studies reporting increased relapse risks.
  • Individualized treatment decisions regarding helicobacter pylori eradication in IBD should consider the complex relationship with gut microbiota.

Cite This Study

Vuković et al. (2025) studied this question.

synapsesocial.com/papers/68c238d2b210217d64779d21https://doi.org/10.3390/jcm14176083
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