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July 14, 2025CellsOpen Access

Regulatory Functions of microRNAs in Cancer Stem Cells: Mechanism, Facts, and Perspectives

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Authors

XMX.S. MaoSPSixue PengYLYan Lu

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Overview

Systematic review reveals microRNAs regulate cancer stem cell characteristics, suggesting new diagnosis and therapy strategies.

Key Points

  • MicroRNAs play a critical role in regulating the characteristics of cancer stem cells, impacting tumor progression.
  • CSCs contribute to tumor heterogeneity and are linked to challenges like drug resistance and metastasis.
  • The molecular mechanisms of miRNAs involve targeting key genes and modulating important signaling pathways.
  • Research explores miRNAs as potential non-invasive biomarkers for cancer diagnosis and prognosis evaluation.

Cite This Study

Mao et al. (2025) studied this question.

synapsesocial.com/papers/689a02b6e6551bb0af8cc268https://doi.org/10.3390/cells14141073
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Emerging Role of Exosome-Derived miRNAs in Cancer and Cancer Stem Cells2025
  2. 2MicroRNAs as Cancer Biomarkers: Unveiling Diagnostic and Prognostic Potential2025
  3. 3Exosomal miRNAs: Key Regulators of the Tumor Microenvironment and Cancer Stem Cells2025
  4. 4Mechanistic Role of circRNAs in Malignant Characterizations of Cancer Stem Cells2025
  5. 5Cancer stem cells in personalized therapy: mechanisms, microenvironment crosstalk, and therapeutic vulnerabilities2025 · 16 citations