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December 4, 2025Journal of Pharmacology and PharmacotherapeuticsOpen Access

Pharmacological Strategies in Cancer Immunotherapy: Advancing Immune Checkpoint Inhibitors, CAR-T Cell Therapies, and Cancer Vaccines

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Authors

PYPankaj YadavBTBhishmani Tarare

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Overview

Narrative review highlights cancer immunotherapy advances via immune checkpoint inhibitors and vaccines, indicating combined therapies may enhance effectiveness in resistant cancers.

Key Points

  • Immunotherapy shows improved anti-tumor immunity in various cancer types, particularly with immune checkpoint inhibitors.
  • Promising results in non-small-cell lung cancer and melanoma suggest a shift in cancer treatment paradigms.
  • Observational analysis of clinical trials emphasizes diverse therapeutic approaches for overcoming resistance mechanisms.
  • Continued innovation in cancer vaccines may broaden applications and boost response rates against solid tumors.

Cite This Study

Yadav et al. (2025) studied this question.

synapsesocial.com/papers/6930dc92ea1aef094cca294ahttps://doi.org/10.1177/0976500x251398611
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