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August 7, 2025Theoretical and Natural Science

The Evolving Landscape of Immunotherapy in Triple-negative Breast Cancer: Mechanisms, Biomarkers, and Future Horizons

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Authors

JLJun Lyu

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Overview

Review synthesizes recent insights on immunotherapy efficacy and biomarkers in triple-negative breast cancer, highlighting significant progress.

Key Points

  • Triple-negative breast cancer is an aggressive form of cancer with limited treatment options historically.
  • Recent studies show that immune checkpoint inhibitors improve overall survival in early-stage triple-negative breast cancer.
  • Antibody-drug conjugates like sacituzumab govitecan are now standard for treating metastatic triple-negative breast cancer.
  • Emerging biomarkers such as TILs are vital for predicting treatment responses and shaping personalized therapies.

Cite This Study

Jun Lyu (2025) studied this question.

synapsesocial.com/papers/689522189f4f1c896c429f08https://doi.org/10.54254/2753-8818/2025.ld25832
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Immunotherapy in breast cancer: current landscape and emerging trends2025 · 7 citations
  2. 2Integrating molecular targeting and immune modulation in triple-negative breast cancer: from mechanistic insights to therapeutic innovation2025 · 5 citations
  3. 3Immunotherapy resistance in triple-negative breast cancer: Molecular mechanisms, tumor microenvironment, and therapeutic implications2025 · 27 citations
  4. 4Neoantigen-Driven Immunotherapy in Triple-Negative Breast Cancer: Emerging Strategies and Clinical Potential2025 · 8 citations
  5. 5Chemotherapeutics as Immune Modulators for the Treatment of Triple-Negative Breast Cancer2026