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When added to statin therapy, ezetimibe resulted in incremental lowering of LDL cholesterol levels and improved cardiovascular outcomes. Moreover, lowering LDL cholesterol to levels below previous targets provided additional benefit. (Funded by Merck; IMPROVE-IT ClinicalTrials.gov number, NCT00202878.).
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Christopher P. Cannon
Political Research Associates
Michael A. Blazing
Brigham and Women's Hospital
Robert P. Giugliano
Clinical Research Institute
New England Journal of Medicine
Harvard University
Brigham and Women's Hospital
Leiden University Medical Center
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Cannon et al. (Thu,) studied this question.
synapsesocial.com/papers/69c3f11d9ffe34c8f287f494 — DOI: https://doi.org/10.1056/nejmoa1410489
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