What is the clinical evidence from this study?

Study design: Case Report. Population: Giant adrenal teratoma during pregnancy with coexisting fetal pulmonary sequestration (n=1). Intervention: Watchful waiting followed by postpartum laparoscopic resection. Primary outcome: Maternal and fetal outcomes.

What does this research mean for the field?

Delaying surgery until the postpartum period is a safe and effective strategy for managing non-functional, non-malignant giant retroperitoneal tumors discovered during pregnancy. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To describe the diagnostic evaluation and surgical management of a giant retroperitoneal adrenal teratoma presenting during pregnancy with concurrent fetal pulmonary sequestration.

September 5, 2026BMC Pregnancy and ChildbirthOpen Access

Giant adrenal teratoma mimicking renal angiomyolipoma during pregnancy with coexisting fetal pulmonary sequestration: a case report

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Key result

Watchful waiting followed by postpartum resection safely manages giant adrenal teratoma with excellent maternal-fetal outcomes.

Key Points

To describe the diagnostic evaluation and surgical management of a giant retroperitoneal adrenal teratoma presenting during pregnancy with concurrent fetal pulmonary sequestration.
Evaluated a 31-year-old primigravida at 12 weeks of gestation presenting with a 9.8 × 13.3 × 10.9 cm fat-containing retroperitoneal mass via MRI and hormonal testing (catecholamines and cortisol).
Adopted a multidisciplinary watchful waiting strategy throughout pregnancy, followed by elective cesarean delivery at 37 + 1 weeks and postpartum elective laparoscopic tumor resection.
Hormone panels confirmed a non-functional tumor, enabling safe postponement of surgical intervention until after delivery.
Postpartum laparoscopic resection achieved complete removal despite IVC encasement and a minor IVC laceration repaired with 200 mL total blood loss; pathology confirmed mature adrenal teratoma with excellent mother and neonate outcomes.

Study Design

Type

Case Report (n=1)

Multicenter

Structured PICO

Population

A 31-year-old pregnant woman presenting with a giant right adrenal teratoma mimicking renal angiomyolipoma and coexisting fetal pulmonary sequestration, managed via a multidisciplinary approach.

Intervention

Multidisciplinary watchful waiting during pregnancy, elective cesarean section at 37+1 weeks, and postpartum elective laparoscopic resection of the retroperitoneal tumor.

This case demonstrates that delaying surgery until the postpartum period is a safe strategy for non-functional giant retroperitoneal tumors during pregnancy, provided multidisciplinary management is utilized.

Limitations

Imaging diagnosis of giant fat-containing retroperitoneal tumors during pregnancy is challenging due to anatomical displacement by the gravid uterus.

Discussion

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Implication

Supports watchful waiting for non-functional retroperitoneal tumors in pregnancy with multidisciplinary care; hypothesis-generating and requires confirmation in larger series.

Cite This Study

Yang et al. (2026) conducted a case report in Giant adrenal teratoma during pregnancy with coexisting fetal pulmonary sequestration (n=1). Watchful waiting followed by postpartum laparoscopic resection was evaluated on Maternal and fetal outcomes. A multidisciplinary strategy of watchful waiting during pregnancy followed by postpartum laparoscopic resection safely managed a giant non-functional adrenal teratoma, resulting in excellent maternal and neonatal outcomes.

synapsesocial.com/papers/6a9bd48c6b95aff0620ec4ad https://doi.org/10.1186/s12884-026-09872-x

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Implication

Supports watchful waiting for non-functional retroperitoneal tumors in pregnancy with multidisciplinary care; hypothesis-generating and requires confirmation in larger series.