What does this research mean for the field?

Concomitant tricuspid valve repair during redo mitral valve replacement is not independently associated with major adverse postoperative events, which are instead primarily driven by patient-related risk factors and operative complexity. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate whether concomitant tricuspid valve repair independently increases major adverse postoperative events following redo mitral valve replacement.

September 4, 2026Journal of Cardiovascular Development and DiseaseOpen Access

Concomitant TVR during redo MVR is not associated with major adverse postoperative events.

Q: What is the clinical evidence from this study?

Study design: Cohort. Population: Redo mitral valve replacement (n=249). Intervention: Concomitant tricuspid valve repair vs. Isolated redo mitral valve replacement. Primary outcome: Major adverse postoperative events (early mortality, acute kidney injury, cerebrovascular event, prolonged ventilation, reoperation, deep sternal infection, mechanical circulatory support, or permanent pacemaker implantation).

View Full Paper

Ask AI

Bookmark

Why the study?

Does concomitant tricuspid valve repair increase major adverse postoperative events in patients undergoing redo mitral valve replacement compared to isolated redo mitral valve replacement?

Population

249 consecutive patients undergoing redo mitral valve replacement between 2019 and 2025.

Comparison

Redo mitral valve replacement with concomitant… vs Isolated redo mitral valve replacement

Design

Cohort

Key result

Concomitant tricuspid valve repair during redo mitral valve replacement was not independently associated with major adverse postoperative events, which occurred in 122 of 249 patients overall.

Authors

BTBarış Timur ZAZinar Apaydın

Discussion

Member takes

Overview

Concomitant tricuspid valve repair during redo mitral valve replacement does not independently increase the risk of major adverse postoperative events, suggesting it can be safely performed when indicated without adding prohibitive risk.

Key Points

To evaluate whether concomitant tricuspid valve repair independently increases major adverse postoperative events following redo mitral valve replacement.
Retrospectively analyzed 249 consecutive patients undergoing redo mitral valve replacement between 2019 and 2025.
Compared isolated redo mitral valve replacement (n=134) with redo mitral valve replacement plus concomitant tricuspid valve repair (n=115).
Assessed a primary composite endpoint of major adverse postoperative events including early mortality, acute kidney injury, stroke, prolonged ventilation, reoperation, infection, mechanical circulatory support, and pacemaker placement.
Major adverse postoperative events occurred in 122 of 249 patients, with similar early mortality observed between groups.
Concomitant tricuspid valve repair was not independently associated with major adverse postoperative events on univariable or multivariable analysis.
Independent risk factors for major adverse events included advanced age, smoking history, lower left ventricular ejection fraction, and longer cardiopulmonary bypass time.

Study Design

Type

Cohort (n=249)

Structured PICO

Does concomitant tricuspid valve repair increase major adverse postoperative events in patients undergoing redo mitral valve replacement compared to isolated redo mitral valve replacement?

Population

249 consecutive patients undergoing redo mitral valve replacement between 2019 and 2025.

Exposure

Redo mitral valve replacement with concomitant tricuspid valve repair

Comparator

Isolated redo mitral valve replacement

Outcome

Major adverse postoperative events (composite of early mortality, acute kidney injury, cerebrovascular event, prolonged ventilation, reoperation, deep sternal infection, mechanical circulatory support, or permanent pacemaker implantation)composite

Cite This Study

Timur et al. (2026) conducted a cohort in Redo mitral valve replacement (n=249). Concomitant tricuspid valve repair vs. Isolated redo mitral valve replacement was evaluated on Major adverse postoperative events (early mortality, acute kidney injury, cerebrovascular event, prolonged ventilation, reoperation, deep sternal infection, mechanical circulatory support, or permanent pacemaker implantation). Concomitant tricuspid valve repair during redo mitral valve replacement was not independently associated with major adverse postoperative events, which occurred in 122 of 249 patients overall.

synapsesocial.com/papers/6a9a85d25d9e33f25c631303 https://doi.org/10.3390/jcdd13090431

View Full Paper

Ask AI

Bookmark

September 4, 2026Journal of Cardiovascular Development and DiseaseOpen Access

Concomitant TVR during redo MVR is not associated with major adverse postoperative events.

View Full Paper

Ask AI

Bookmark

Why the study?

Does concomitant tricuspid valve repair increase major adverse postoperative events in patients undergoing redo mitral valve replacement compared to isolated redo mitral valve replacement?

Population

249 consecutive patients undergoing redo mitral valve replacement between 2019 and 2025.

Comparison

Redo mitral valve replacement with concomitant… vs Isolated redo mitral valve replacement

Design

Cohort

Key result

Concomitant tricuspid valve repair during redo mitral valve replacement was not independently associated with major adverse postoperative events, which occurred in 122 of 249 patients overall.

Authors

BTBarış Timur ZAZinar Apaydın

Discussion

Member takes

Overview

Key Points

To evaluate whether concomitant tricuspid valve repair independently increases major adverse postoperative events following redo mitral valve replacement.
Retrospectively analyzed 249 consecutive patients undergoing redo mitral valve replacement between 2019 and 2025.
Compared isolated redo mitral valve replacement (n=134) with redo mitral valve replacement plus concomitant tricuspid valve repair (n=115).
Assessed a primary composite endpoint of major adverse postoperative events including early mortality, acute kidney injury, stroke, prolonged ventilation, reoperation, infection, mechanical circulatory support, and pacemaker placement.
Major adverse postoperative events occurred in 122 of 249 patients, with similar early mortality observed between groups.
Concomitant tricuspid valve repair was not independently associated with major adverse postoperative events on univariable or multivariable analysis.
Independent risk factors for major adverse events included advanced age, smoking history, lower left ventricular ejection fraction, and longer cardiopulmonary bypass time.

Study Design

Type

Cohort (n=249)

Structured PICO

Does concomitant tricuspid valve repair increase major adverse postoperative events in patients undergoing redo mitral valve replacement compared to isolated redo mitral valve replacement?

Population

249 consecutive patients undergoing redo mitral valve replacement between 2019 and 2025.

Exposure

Redo mitral valve replacement with concomitant tricuspid valve repair

Comparator

Isolated redo mitral valve replacement

Outcome

Cite This Study

synapsesocial.com/papers/6a9a85d25d9e33f25c631303 https://doi.org/10.3390/jcdd13090431

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

View Full Paper

Ask AI

Bookmark