What does this research mean for the field?

The coexistence of left and right ventricular dysfunction significantly impacts 1-year prognostic outcomes following transcatheter aortic valve replacement. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To assess the prognostic significance and 1-year clinical outcomes associated with coexisting left and right ventricular dysfunction in patients undergoing transcatheter aortic valve replacement.

September 3, 2026JACC AsiaOpen Access

Combined LV and RV dysfunction in aortic stenosis carries uncertain prognostic significance after TAVR.

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Key result

Combined left and right ventricular dysfunction presents as overlapping but distinct functional profiles in aortic stenosis, with uncertain prognostic significance after TAVR.

Authors

YLYingqi Liu ZGZhenyi Ge ZGZhenyi Ge

Discussion

Member takes

Overview

Biventricular dysfunction may refine post-TAVR risk stratification; leaves open whether myocardial-targeted therapies improve outcomes beyond valve replacement.

Key Points

To assess the prognostic significance and 1-year clinical outcomes associated with coexisting left and right ventricular dysfunction in patients undergoing transcatheter aortic valve replacement.
Characterized functional left ventricular (LV) and right ventricular (RV) dysfunction profiles in patients undergoing transcatheter aortic valve replacement (TAVR) for severe aortic stenosis.
Tracked post-procedural clinical outcomes to assess the cumulative impact of biventricular myocardial impairment across 1 year of follow-up.
Left and right ventricular dysfunction manifest as distinct yet overlapping functional profiles in patients with severe aortic stenosis.
Post-TAVR outcomes reflect cumulative, underlying myocardial injury that extends beyond the relief of primary valvular stenosis.

Cite This Study

Liu et al. (2026) studied this question. Combined left and right ventricular dysfunction presents as overlapping but distinct functional profiles in aortic stenosis, with uncertain prognostic significance after TAVR.

synapsesocial.com/papers/6a9935b1636c6408cfa7e1cd https://doi.org/10.1016/j.jacasi.2026.07.015

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September 3, 2026JACC AsiaOpen Access

Combined LV and RV dysfunction in aortic stenosis carries uncertain prognostic significance after TAVR.

View Full Paper

Ask AI

Bookmark

Key result

Combined left and right ventricular dysfunction presents as overlapping but distinct functional profiles in aortic stenosis, with uncertain prognostic significance after TAVR.

Authors

YLYingqi Liu ZGZhenyi Ge ZGZhenyi Ge

Discussion

Member takes

Overview

Biventricular dysfunction may refine post-TAVR risk stratification; leaves open whether myocardial-targeted therapies improve outcomes beyond valve replacement.

Key Points

To assess the prognostic significance and 1-year clinical outcomes associated with coexisting left and right ventricular dysfunction in patients undergoing transcatheter aortic valve replacement.
Characterized functional left ventricular (LV) and right ventricular (RV) dysfunction profiles in patients undergoing transcatheter aortic valve replacement (TAVR) for severe aortic stenosis.
Tracked post-procedural clinical outcomes to assess the cumulative impact of biventricular myocardial impairment across 1 year of follow-up.
Left and right ventricular dysfunction manifest as distinct yet overlapping functional profiles in patients with severe aortic stenosis.
Post-TAVR outcomes reflect cumulative, underlying myocardial injury that extends beyond the relief of primary valvular stenosis.

Cite This Study

synapsesocial.com/papers/6a9935b1636c6408cfa7e1cd https://doi.org/10.1016/j.jacasi.2026.07.015

View Full Paper

Ask AI

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