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August 27, 2026Discover OncologyOpen Access

Minimally invasive surgical and endoscopic management of esophageal leiomyoma

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Authors

BLBowei LiuCSCheng ShenJZJian-Feng Zhou

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Overview

Clinical review reveals minimally invasive techniques reduce morbidity for esophageal leiomyoma, highlighting the value of personalized, size-adapted decision algorithms.

Key Points

  • To review minimally invasive surgical and endoscopic treatment modalities for esophageal leiomyoma and synthesize an evidence-based clinical management algorithm.
  • Reviewed multicenter clinical evidence across endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD), submucosal tunneling endoscopic resection (STER), and robotic techniques.
  • Evaluated perioperative innovations—such as CO₂ insufflation, intraoperative endoscopy, and ERAS protocols—using GRADE-informed evidence assessments.
  • Minimally invasive and robotic enucleation approaches show early evidence of reduced postoperative morbidity and shorter hospital stays compared to open thoracotomy.
  • A structured decision algorithm integrating tumor size, anatomical location, morphology, and growth dynamics refines procedural selection.
  • Identified critical gaps in current literature, specifically a lack of prospective randomized validation, long-term comparative outcomes, and comprehensive cost-effectiveness data.

Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/6a8fe96710c91c1e92620f4ahttps://doi.org/10.1007/s12672-026-05789-1
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