Diagnostic accuracy of glycated albumin and fructosamine for detecting diabetes and prediabetes in adults: a systematic review and meta-analysis protocol
Systematic review evaluates diagnostic accuracy of glycated albumin and fructosamine for diabetes detection, highlighting clinical implications.
Key Points
This review aims to assess the diagnostic accuracy of glycated albumin and fructosamine for detecting diabetes and prediabetes compared to the oral glucose tolerance test.
Systematic review and meta-analysis following PRISMA-DTA guidelines.
Databases searched include MEDLINE, Scopus, and Web of Science from inception to December 2025.
Studies evaluating glycated albumin or fructosamine against OGTT in adult populations will be included.
This review will provide pooled diagnostic accuracy measures for GA and FA.
Hierarchical summary receiver operating characteristic curves will be constructed to analyze results.
The findings will clarify the potential use of GA and FA as alternatives to HbA1c.