Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 26, 2026Clinical Endocrinology

Reassessing the Luteinizing Hormone/Follicle‐Stimulating Hormone Ratio in Polycystic Ovary Syndrome: Associations With a Possible Neuroendocrine and Anti‐Müllerian Hormone‐Related Phenotype

View Full Paper
Ask AI
Bookmark
Share

Authors

MYMert YeşiladalıMYMelis Gökce Kocer YaziciZKZeynep Ece Utkan Korun

Discussion

Loading...

Member takes

Overview

Observational study investigates LH:FSH ratio and its implications for neuroendocrine phenotypes in PCOS.

Key Points

  • This research aims to reassess the significance of the LH:FSH ratio in PCOS and explore its associations with neuroendocrine features.
  • Conducted a retrospective cross-sectional study with 316 women diagnosed with PCOS based on the Rotterdam criteria.
  • Categorized patients by LH:FSH ratio cut-off of 2 and evaluated hormonal and metabolic parameters, including AMH levels.
  • Compared clinical characteristics across different PCOS phenotypes (A, B, C, D).
  • 18.35% of patients had an LH:FSH ratio >2, correlating strongly with AMH levels (r = 0.65, p < 0.001).
  • Higher LH:FSH ratios linked to clinical features like oligo/amenorrhea and anovulation, not with serum androgens.
  • Insulin levels showed a weak positive correlation with LH:FSH ratios (ρ = 0.18, p = 0.022) but no significant links to BMI or lipid profiles.

Cite This Study

Yeşiladalı et al. (2026) studied this question.

synapsesocial.com/papers/6a65a36cd3aea3239cd769aehttps://doi.org/10.1111/cen.70179
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Leptin and LH/FSH ratio as independent predictors of polycystic ovary syndrome in normoglycemic women: a case-control study2025
  2. 2Luteinizing Hormone Levels as a Biological Mechanism for Polycystic Ovary Syndrome2025
  3. 3Polycystic Ovary Syndrome: The Interplay Between Ovarian Morphology, Hyperandrogenism, and Metabolic Health2024
  4. 4The relationship of antimullerian hormone with severity of clinical symptoms in polycystic ovary syndrome2025
  5. 5Anti-Mullerian Hormone as a Surrogate Diagnostic Marker for Polycystic Ovary Syndrome2025