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July 26, 2026Annals of Clinical Microbiology and AntimicrobialsOpen Access

Multi-drug resistance and multiple antibiotic resistance index of uropathogens in diabetic and non-diabetic patients with urinary tract infections

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Authors

PKPriyal KalolaHPHemantkumar PatadiaAPAnkita Priyadarshini

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Overview

Prospective study assesses multidrug resistance in uropathogens of diabetic and non-diabetic patients, suggesting urgent need for tailored treatments.

Key Points

  • This study aims to evaluate the rates of multidrug resistance (MDR) and multiple antibiotic resistance index (MARI) among uropathogens in diabetic versus non-diabetic patients with urinary tract infections (UTIs).
  • Prospective study conducted from August 2021 to January 2024 in Gujarat, India.
  • Involved 2,408 patients with UTI symptoms, with 954 testing positive for UTIs.
  • Analyzed antibiotic resistance patterns in diabetic (280) and non-diabetic (674) UTI patients.
  • 61.84% of uropathogens were multidrug resistant (MDR) with higher rates in diabetic patients (92.10% for P. aeruginosa).
  • MARI greater than 0.2 was observed in 87.01% of gram-negative uropathogens in diabetics and 71.03% in non-diabetics.
  • E. coli showed 70.99% MDR in non-diabetics, indicating significant differences in prevalence and resistance patterns.

Cite This Study

Kalola et al. (2026) studied this question.

synapsesocial.com/papers/6a65a36cd3aea3239cd76861https://doi.org/10.1186/s12941-026-00866-3
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Antimicrobial resistance of uropathogens in diabetic patients2025 · 5 citations
  2. 2Hospital Admissions and Antimicrobial Resistance Patterns in Diabetic Patients With Urinary Tract Infections: A Cross-Sectional Study From a Tertiary Care Center in Pakistan2025
  3. 3Investigation of some bacterial causes of urinary tract infection in diabetic patients in Al-Muthanna Province2025
  4. 4A-264 Urine Culture Trends from 2022 to 2025: A Review of Microorganism Prevalence2025
  5. 5Comparison Between Urinary Tract Infection Bacteriuria in Diabetic and Non-Diabetic Patients Identified by VITEK 2 and 16S rRNA Sequencing Against Some Biological Factors2025