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July 24, 2026PLoS ONEOpen Access

Sociodemographic and psychosocial factors are linked to medication literacy, which is low in ~35% of younger hypertensives.

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Why the study?

What are the profiles of medication literacy and their associated factors among young and middle-aged hypertensive patients in China?

Population

544 young and middle-aged hypertensive patients consecutively recruited from two tertiary hospitals in China

Design

Cross-sectional

Key result

Sociodemographic and psychosocial factors were significantly associated with medication literacy profiles (low 35.3%, moderate 50.2%, high 14.5%) among young and middle-aged hypertensive patients (p<0.05).

Authors

RWR L WangCLChongbin LiuYWYu Wang

Discussion

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Overview

Sociodemographic factors may identify hypertensive patients needing literacy support; cross-sectional data leave causal effects and intervention targets open for prospective study.

Key Points

  • This study aims to identify distinct profiles of medication literacy among young and middle-aged hypertensive patients in China and explore their associated factors.
  • Cross-sectional study with 544 hypertensive patients from two hospitals in China.
  • Five validated instruments were used to assess medication literacy and associated factors.
  • Latent profile analysis and multivariate logistic regression were conducted to identify profiles and associated factors.
  • Three profiles of medication literacy were identified: low (35.3%), moderate (50.2%), and high (14.5%).
  • Education level, income, social support, self-efficacy, and illness perception were significantly associated with medication literacy (all p < 0.05).
  • Lower education and income were linked to low literacy, while higher social support and self-efficacy were associated with high literacy.

Study Design

Type

Cross-Sectional (n=544)

Multicenter

Yes

Structured PICO

What are the profiles of medication literacy and their associated factors among young and middle-aged hypertensive patients in China?

P
Population
544 young and middle-aged hypertensive patients recruited from two tertiary hospitals in China.
O
Outcome
Distinct profiles of medication literacy and associated factors (education level, income, social support, self-efficacy, illness perception)patient reported

Main Result

p-value: p=<0.05

Medication literacy among young and middle-aged hypertensive patients in China is heterogeneous, with socioeconomic and psychosocial factors significantly influencing literacy profiles, suggesting a need for stratified interventions.

Limitations

  • Causal interpretations are precluded by the cross-sectional design

Cite This Study

Wang et al. (2026) conducted a cross-sectional in hypertension (n=544). Sociodemographic and psychosocial factors (education, income, social support, self-efficacy, illness perception) was evaluated on Medication literacy profiles (p=<0.05). Sociodemographic and psychosocial factors were significantly associated with medication literacy profiles (low 35.3%, moderate 50.2%, high 14.5%) among young and middle-aged hypertensive patients (p<0.05).

synapsesocial.com/papers/6a63008d395161722cd157a3https://doi.org/10.1371/journal.pone.0352857
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Association between health literacy and medication adherence in patients with hypertension: a cross-sectional study2025 · 7 citations
  2. 2Measuring the medication literacy level of community residents: a cross-sectional study2025
  3. 3Characteristics and influencing factors of self-management behaviors of hypertensive patients in areas with concentrated ethnic minorities on plateau: a latent profile analysis2026
  4. 4Latent profile and determinants of digital health literacy among older adult patients with chronic diseases: a cross-sectional study2025 · 12 citations
  5. 5Analysis of potential profiles of health literacy in chronic heart failure patients2025