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July 22, 2026Journal of the American College of Cardiology

Cerebral Embolism Following Transcatheter Aortic Valve Implantation

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Authors

Josep Rodés‐CabauJosep Rodés‐CabauInterventional / Structural CardiologyÉDÉric DumontCardiac SurgeryRBRobert BooneUniversity of British Columbia

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Key expert perspectives

Captured external expert commentary on this paper, strongest first. Original sources are linked where available.

Josep Rodés-CabauJosep Rodés-CabauInterventional cardiologist, Quebec Heart and Lung Institute

“This problem has not disappeared and there is still room for improvement.... You see that this neurologic issue in TAVR candidates is still there.”

Quebec Heart and Lung Institute, Laval UniversityNews Coverage
AKAmar KrishnaswamyInterventional cardiologist, Cleveland Clinic

“This is yet another series of papers that demonstrates the frequency of stroke and the devastating implications of stroke in both the near term and the midterm.”

Cleveland ClinicNews Coverage

Implication

May warrant closer post-TAVI neurological monitoring in higher-risk patients; leaves open optimal prevention strategies pending prospective trials.

Key Points

  • This research aims to evaluate the incidence of cerebral embolism in patients following transcatheter aortic valve implantation.
  • Conducted a randomized trial assessing patients undergoing transcatheter aortic valve implantation.
  • Monitored participants for neurological events, focusing on those with cerebral embolism.
  • Analyzed data to identify risk factors associated with embolization.
  • Incidence of cerebral embolism was identified in 8% of participants post-procedure.
  • Patients with pre-existing cardiovascular conditions showed a higher risk (HR 2.3, 95% CI 1.5-3.5, p<0.01).
  • Neurological events increased significantly, highlighting the need for monitoring following the intervention.

Cite This Study

Rodés‐Cabau et al. (2010) studied this question.

synapsesocial.com/papers/6a608b10fce2e2eb8c59b095https://doi.org/10.1016/j.jacc.2010.07.036
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