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July 18, 2026European Journal of Cardiovascular Nursing

Worse gastrointestinal symptoms strongly correlate with poorer quality of life in heart failure patients.

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Why the study?

Is gastrointestinal symptom severity associated with quality of life in patients with heart failure?

Population

180 patients with heart failure, mean age 69.46 ± 13.22 years, 61.1% male.

Design

Cross-sectional

Key result

Gastrointestinal symptom severity was significantly correlated with poorer quality of life in patients with heart failure (r = 0.57; p < 0.05).

Authors

YUY Kalkan UgurluAAA Aksu

Discussion

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Overview

GI symptoms associated with poorer HF QoL; hypothesis-generating and requires prospective validation before practice change.

Key Points

  • The study aims to explore how the severity of gastrointestinal symptoms affects the quality of life in heart failure patients.
  • Conducted a descriptive and correlational study with 180 patients from December 2024 to March 2025.
  • Used the Gastrointestinal Symptom Rating Scale (GSRS) and Minnesota Living with Heart Failure Questionnaire (MLHFQ) for data collection.
  • Analyzed data using SPSS and accepted statistical significance at p<0.05.
  • Total MLHFQ score shows a positive correlation with GSRS (r = 0.57; p < 0.05).
  • Increased severity of indigestion (p = 0.000), constipation (p = 0.000), and abdominal pain (p = 0.018) correlates with a decline in quality of life.

Study Design

Type

Cross-Sectional (n=180)

Structured PICO

Is gastrointestinal symptom severity associated with quality of life in patients with heart failure?

P
Population
180 patients with heart failure (mean age 69.5 years, 38.9% female) assessed for the relationship between gastrointestinal symptoms and quality of life.
O
Outcome
Correlation between gastrointestinal symptom severity (measured by Gastrointestinal Symptom Rating Scale) and quality of life (measured by Minnesota Living with Heart Failure Questionnaire)patient reported

Main Result

Effect estimate: r = 0.57

p-value: p=< 0.05

In patients with heart failure, the severity of gastrointestinal symptoms—particularly indigestion, constipation, and abdominal pain—is significantly associated with a decline in quality of life.

Cite This Study

Ugurlu et al. (2026) conducted a cross-sectional in Heart failure (n=180). Gastrointestinal symptom severity was evaluated on Quality of life (MLHFQ score) (r = 0.57, p=< 0.05). Gastrointestinal symptom severity was significantly correlated with poorer quality of life in patients with heart failure (r = 0.57; p < 0.05).

synapsesocial.com/papers/6a5b38f68167787360d24e49https://doi.org/10.1093/eurjcn/zvag155.018
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