Population
Patients with hypertrophic cardiomyopathy (HCM)
Design
Review
Key result
Women with hypertrophic cardiomyopathy are diagnosed later and present with more advanced symptoms, greater left ventricular outflow tract obstruction, and worse heart failure burden compared to men.
Authors
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Current sex-neutral HCM risk tools may underestimate severity in women; leaves open whether sex-specific adjustments improve outcomes.
Women with hypertrophic cardiomyopathy face delayed diagnosis and worse heart failure progression, underscoring the need for sex-specific risk assessment and management strategies.
Abraham et al. (2026) conducted a review in Hypertrophic cardiomyopathy. Female sex vs. Male sex was evaluated. Women with hypertrophic cardiomyopathy are diagnosed later and present with more advanced symptoms, greater left ventricular outflow tract obstruction, and worse heart failure burden compared to men.