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July 11, 2026European Heart Journal - Case ReportsOpen Access

Intracoronary vasodilators and tailored drug therapy terminate refractory VF storm in a multivessel spasm patient.

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Why the study?

Does intracoronary vasodilator therapy combined with personalized drug adjustment terminate refractory ventricular fibrillation storms in patients with multivessel vasospastic angina?

Population

A 67-year-old man with multivessel vasospastic angina and prior subcutaneous ICD who experienced…

Design

Case_report

Key result

Intracoronary vasodilator therapy combined with personalised drug adjustment successfully terminated refractory ventricular fibrillation storm and prevented recurrence in a patient with multivessel spasm.

Authors

AIAya IshigakiMKMasashi KogaYSYukio Satô

Discussion

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Overview

May offer rescue option for refractory VF in multivessel spasm; leaves open need for prospective trials before practice change.

Key Points

  • This report aims to explore a novel approach for treating refractory ventricular fibrillation storms triggered by multivessel coronary spasm.
  • Case analysis of a 67-year-old man with VF secondary to vasospastic angina.
  • Intervention involved intracoronary vasodilator therapy and tailored adjustment of oral medications.
  • Coronary angiography was used to confirm the presence of multivessel spasms.
  • Intracoronary vasodilator administration halted recurrent VF after failed external defibrillation.
  • Tailored optimisation of oral vasodilator therapy prevented further VF episodes.
  • Patient remained stable without recurrent events for the follow-up period.

Study Design

Type

Case Report (n=1)

Structured PICO

Does intracoronary vasodilator therapy combined with personalized drug adjustment terminate refractory ventricular fibrillation storms in patients with multivessel vasospastic angina?

P
Population
A 67-year-old man with refractory ventricular fibrillation storm triggered by multivessel coronary spasm.
I
Intervention
Intracoronary vasodilator administration followed by defibrillation and subsequent tailored optimization of oral vasodilator therapy.
O
Outcome
Termination of ventricular fibrillation and prevention of recurrence.

Intracoronary vasodilator therapy combined with personalized drug adjustment may represent a valuable therapeutic option for refractory VF storms triggered by multivessel coronary spasm.

Cite This Study

Ishigaki et al. (2026) conducted a case report in Refractory ventricular fibrillation storm triggered by multivessel coronary spasm (n=1). Intracoronary vasodilator administration and tailored optimisation of oral vasodilator therapy was evaluated on Termination of VF and prevention of recurrence. Intracoronary vasodilator therapy combined with personalised drug adjustment successfully terminated refractory ventricular fibrillation storm and prevented recurrence in a patient with multivessel spasm.

synapsesocial.com/papers/6a51df22c18d7f28ca5007cchttps://doi.org/10.1093/ehjcr/ytag506
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