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July 11, 2026BMC Public HealthOpen Access

HIV vulnerability among adolescent girls and young women in sub-Saharan Africa: a systematic review of individual social and structural determinants

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Authors

PMPatrick MukokomaB-Basake Julius Alochere -LNLekia Nkpordee

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Overview

Systematic review examines factors influencing HIV vulnerability in young women, highlighting the need for integrated prevention strategies.

Key Points

  • This review aims to synthesize individual, interpersonal, and structural determinants influencing HIV vulnerability among adolescent girls and young women in sub-Saharan Africa.
  • Conducted a systematic review according to PRISMA 2020 guidelines.
  • Searched five electronic databases for studies on HIV vulnerability determinants in AGYW.
  • Synthesized findings using a social ecological framework; meta-analysis performed on comparable quantitative data.
  • Age discordant partnerships, transactional sex, and intimate partner violence were associated with increased HIV vulnerability, with pooled estimates indicating elevated risks.
  • Poverty, food insecurity, school dropout, and migration were identified as consistent structural drivers of vulnerability.
  • Low perceived susceptibility to HIV and inconsistent condom use were common risk behaviors linked to gender power imbalances.

Cite This Study

Mukokoma et al. (2026) studied this question.

synapsesocial.com/papers/6a51dd5ac18d7f28ca4fffefhttps://doi.org/10.1186/s12889-026-28416-8
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