Why the study?
Does treatment of iron deficiency anemia improve subclinical biventricular dysfunction in children?
Population
69 children (40 with predominantly mild-to-moderate iron deficiency anemia and 29 healthy controls)
Comparison
Anemia treatment vs Pre-treatment baseline and healthy controls
Design
Case-control
Key result
Treatment of iron deficiency anemia in children improved left and right ventricular longitudinal strain and tissue Doppler parameters, though some subtle myocardial alterations persisted.
Authors
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Persistent subtle biventricular changes may remain after iron repletion in children; leaves open whether long-term surveillance improves outcomes.
Case-Control (n=69)
Does treatment of iron deficiency anemia improve subclinical biventricular dysfunction in children?
Treatment of iron deficiency anemia in children improves subclinical biventricular dysfunction as assessed by advanced echocardiography, though some subtle alterations may persist.
Zorlu et al. (2026) conducted a case-control in iron deficiency anemia (n=69). Iron deficiency anemia vs. Healthy controls was evaluated on biventricular function assessed by two-dimensional speckle-tracking echocardiography and tissue Doppler imaging. Treatment of iron deficiency anemia in children improved left and right ventricular longitudinal strain and tissue Doppler parameters, though some subtle myocardial alterations persisted.