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July 3, 2026Journal of Thrombosis and Thrombolysis

Figure-of-eight suturing reduces time to hemostasis post-ablation without increasing complications versus manual compression.

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Why the study?

Does figure-of-eight suturing improve safety and procedural outcomes compared to manual compression for femoral venous hemostasis in patients undergoing atrial fibrillation ablation?

Population

2,125 patients from 9 studies undergoing atrial fibrillation ablation requiring femoral venous hemostasis

Comparison

Figure-of-eight suturing for post-ablation… vs Manual compression for post-ablation femoral…

Design

Meta-analysis

Key result

Figure-of-eight suturing was as safe as manual compression for post-ablation femoral venous hemostasis, showing no increase in complications while significantly reducing time to hemostasis.

Authors

ZBZaryab BachaJJJaveria JavedMKMuhammad Hamad Khan

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Overview

Supports faster post-ablation hemostasis without added complications; strengthens Level 1 evidence for figure-of-eight suturing.

Key Points

  • This research aims to compare the safety and efficacy of figure-of-eight sutures versus manual compression for femoral venous hemostasis post-ablation.
  • Systematic literature search across multiple databases up to February 2026.
  • Included randomized controlled trials and observational cohort studies comparing Fo8 sutures with manual compression.
  • Meta-analysis performed using RevMan software version 5.4, with data extracted and quality assessed by independent reviewers.
  • No significant differences in total, major, or minor complications, bleeding, or hematoma between Fo8 suturing and manual compression.
  • Fo8 suturing resulted in shorter time to hemostasis and earlier ambulation.
  • Reduced discharge time was observed with figure-of-eight suturing compared to manual compression.

Study Design

Type

Meta-Analysis (n=2,125)

Structured PICO

Does figure-of-eight suturing improve safety and procedural outcomes compared to manual compression for femoral venous hemostasis in patients undergoing atrial fibrillation ablation?

P
Population
2,125 patients across 9 studies undergoing catheter ablation for atrial fibrillation, comparing figure-of-eight sutures versus manual compression for femoral venous hemostasis.
I
Intervention
Figure-of-eight (Fo8) suturing for post-ablation femoral venous hemostasis
C
Comparator
Manual compression for post-ablation femoral venous hemostasis
O
Outcome
Safety and procedural outcomes (total, major, or minor vascular access site complications, bleeding, hematoma, time to hemostasis, time to ambulation, and time to discharge)safety

Figure-of-eight suturing is as safe as manual compression for femoral venous hemostasis after atrial fibrillation ablation, with the added benefits of faster hemostasis, earlier ambulation, and reduced discharge time.

Cite This Study

Bacha et al. (2026) conducted a meta-analysis in Atrial fibrillation (n=2,125). Figure-of-eight sutures vs. Manual compression was evaluated on Vascular access site complications, bleeding, hematoma, and time to hemostasis. Figure-of-eight suturing was as safe as manual compression for post-ablation femoral venous hemostasis, showing no increase in complications while significantly reducing time to hemostasis.

synapsesocial.com/papers/6a4758f85c29257aa257ae30https://doi.org/10.1007/s11239-026-03347-8
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