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July 3, 2026Journal of Brown Hospital MedicineOpen Access

Electroconvulsive therapy linked to Takotsubo cardiomyopathy with 36% LVEF in a patient with CAD.

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Population

1 middle-aged woman with coronary artery disease (CAD), bipolar disorder, and remote tobacco use

Design

Case_report

Key result

Electroconvulsive therapy triggered Takotsubo cardiomyopathy with a left ventricular ejection fraction of 36% in a 67-year-old woman with coronary artery disease and bipolar disorder.

Authors

MNMy Anh NguyenGMGabrielle MontalbanoPAPinar Arikan

Discussion

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Overview

May warrant caution with ECT in CAD patients; extends known TCM triggers but remains hypothesis-generating.

Key Points

  • To investigate the incidence and implications of Takotsubo cardiomyopathy induced by electroconvulsive therapy.
  • Presented a case of a middle-aged woman with CAD and bipolar disorder developing chest pain after ECT.
  • Utilized transthoracic echocardiography to measure LVEF and observe cardiac function.
  • Managed the patient supportively with follow-up by cardiology and psychiatry.
  • Transthoracic echocardiography showed a left ventricular ejection fraction of 36%.
  • The case illustrates ECT-induced Takotsubo cardiomyopathy as an uncommon yet significant complication.
  • Emphasizes the need for thorough evaluation and cardiovascular management prior to ECT resumption.

Study Design

Type

Case Report (n=1)

Multicenter

No

Structured PICO

P
Population
A 67-year-old woman with coronary artery disease, bipolar disorder, and concurrent stimulant therapy who developed Takotsubo cardiomyopathy after her first electroconvulsive therapy session.
I
Intervention
Electroconvulsive therapy (ECT) (first outpatient session)
O
Outcome
Development of Takotsubo cardiomyopathy (TCM)

Electroconvulsive therapy can rarely trigger Takotsubo cardiomyopathy, highlighting the need for clinical recognition and multidisciplinary evaluation in patients with cardiovascular risk factors.

Limitations

  • Single case report
  • Limited generalizability
  • Cannot establish definitive causality

Cite This Study

Nguyen et al. (2026) conducted a case report in Takotsubo cardiomyopathy (n=1). Electroconvulsive therapy was evaluated on Development of Takotsubo cardiomyopathy. Electroconvulsive therapy triggered Takotsubo cardiomyopathy with a left ventricular ejection fraction of 36% in a 67-year-old woman with coronary artery disease and bipolar disorder.

synapsesocial.com/papers/6a4753885c29257aa2579acbhttps://doi.org/10.56305/001c.162048
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Takotsubo Cardiomyopathy Triggered by Emotional Stress in an Elderly Female2025 · 1 citations
  2. 2Usefulness of a Left Ventriculogram in Patients Presenting With Acute Coronary Syndrome Due to Takotsubo Cardiomyopathy: A Case Series2025 · 1 citations
  3. 3Takotsubo Cardiomyopathy–Induced Conduction System Quiescence With Concomitant Fascicular Ventricular Tachycardia and Complete Heart Block2026
  4. 4Abstract Fri090: Recent Evidence on Life-Threatening Arrhythmias in Takotsubo Cardiomyopathy: An Updated Meta-Analysis of Incidence and Outcomes2025
  5. 5Takotsubo Cardiomyopathy in an Elderly Gravida with Twin Gestation2025