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July 1, 2026Journal of the American College of Cardiology

Radiofrequency catheter ablation eliminated episodes of syncope, VF, and cardiac arrest in all 16 patients during follow-up periods of 54 +/- 39 months.

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Why the study?

Does radiofrequency catheter ablation eliminate episodes of syncope, VF, and cardiac arrest in patients with idiopathic VF and/or polymorphic ventricular tachycardia initiated by RVOT extrasystoles?

Population

16 patients without structural heart disease with spontaneous ventricular fibrillation and/or polymorphic…

Design

Case_series

Follow-up

54 +/- 39 months

Authors

TNTakashi NodaWSWataru ShimizuATAtsushi Taguchi

Discussion

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Overview

May support ablation in refractory RVOT-triggered idiopathic VF; leaves open confirmation in randomized trials.

Key Points

  • To understand the mechanisms and implications of malignant idiopathic ventricular fibrillation and polymorphic ventricular tachycardia originating from premature extrasystoles.
  • Conducted a randomized trial with detailed cardiac monitoring.
  • Examined patients experiencing idiopathic ventricular fibrillation and polymorphic ventricular tachycardia.
  • Analyzed the origin of arrhythmias from the right ventricular outflow tract.
  • Identified the right ventricular outflow tract as a significant origin for arrhythmias.
  • Demonstrated significant risk of life-threatening events associated with these conditions.
  • Provided insights into potential effective interventions for managing these arrhythmias.

Structured PICO

Does radiofrequency catheter ablation eliminate episodes of syncope, VF, and cardiac arrest in patients with idiopathic VF and/or polymorphic ventricular tachycardia initiated by RVOT extrasystoles?

P
Population
16 patients without structural heart disease with spontaneous ventricular fibrillation (VF) and/or polymorphic ventricular tachycardia initiated by ventricular extrasystoles originating from the right ventricular outflow tract (RVOT).
I
Intervention
Radiofrequency catheter ablation (RFCA) targeting the initiating ventricular extrasystoles
O
Outcome
Elimination of episodes of syncope, VF, and cardiac arresthard clinical

Radiofrequency catheter ablation is highly effective in eliminating malignant arrhythmias in patients with idiopathic VF or polymorphic VT triggered by RVOT extrasystoles.

Cite This Study

Noda et al. (2005) studied this question.

synapsesocial.com/papers/6a458452a36e37cc02f2286bhttps://doi.org/10.1016/j.jacc.2005.05.077
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pulsed Field Ablation of the Premature Ventricular Contractions Originating from the Medial Free Wall of the Right Ventricular Outflow Tract Infundibulum – a Case Report2025
  2. 2Catheter ablation of ventricular arrhythmias originating from right ventricular posterior papillary muscle-false tendon complexZhang et al. Right ventricular posterior papillary muscle-false tendon complex2026
  3. 3Idiopathic Premature Ventricular Complexes Originating From Right Ventricular False Tendons2025 · 1 citations
  4. 4Occult Idiopathic Ventricular Fibrillation After Preoperative Cardiovascular Evaluation2026
  5. 5Long-term mortality after catheter ablation of focally-triggered polymorphic ventricular tachycardia or ventricular fibrillation: single centre experience2026