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June 28, 2026Journal of Alzheimer s DiseaseOpen Access

Postoperative changes in cervical hemodynamics and cognitive function following cervical lymphatic-venous surgery in Alzheimer's disease

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Authors

XZXiaoju ZhengCTCong TangHLHaijun Li

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Overview

Randomized trial evaluates cervical hemodynamics and cognitive function improvements in Alzheimer's patients, suggesting potential benefits of surgery.

Key Points

  • This research aims to assess the effects of cervical lymphatic-venous surgery on blood flow and cognitive function in Alzheimer's disease patients.
  • Eighty-three Alzheimer's disease patients underwent bilateral cervical lymphatic-venous anastomosis.
  • Pre- and postoperative evaluations included Doppler ultrasound and standardized cognitive assessments.
  • Morphologic and hemodynamic changes were analyzed using the Wilcoxon and Spearman methods.
  • Postoperatively, significant increases in venous and arterial flow were observed.
  • Internal jugular and carotid cross-sectional areas enlarged after surgery.
  • Cognitive function improvements correlated moderately with postoperative carotid flow and sustained for up to 9 months.

Cite This Study

Zheng et al. (2026) studied this question.

synapsesocial.com/papers/6a40bb4561bb0a67205c6e36https://doi.org/10.1177/13872877261459037
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A surgical therapy for Alzheimer's disease with lymphaticovenular anastomosis2025
  2. 2Six Month Study of Therapeutic Effects of Deep Cervical Lymphaticovenular Anastomosis in an Alzheimer's Disease Patient: A Case Report2025
  3. 3Modified Dynamic Lymphaticovenular Anastomosis for Surgical Management of Alzheimer Disease2025
  4. 4Clinical Study of 60 Cases of Deep Cervical Lymphatic-Venous Anastomosis for the Treatment of Alzheimer’s Disease2025
  5. 5"Exploring Lymphovenous Anastomosis for Alzheimer's Disease: Addressing Brain Lymphatic Dysfunction, Feasibility, and Outcome Metrics".2025