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June 27, 2026EP EuropaceOpen Access

For LAAC due to bleeding risk, DAPT was the most frequent discharge regimen (47.9%), while for stroke prevention, DOAC was preferred (41.1%).

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Population

140 physicians from more than 20 countries participating in an EHRA survey on LAAC practice patterns.

Design

Cross-sectional

Authors

LUL UrbanekPFP FutymaMMM Mazurek

Discussion

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Overview

Observed LAAC discharge variation warrants caution in practice; leaves open optimal regimens for randomized evaluation.

Key Points

  • This survey aims to capture current practices regarding antithrombotic strategies following left atrial appendage closure (LAAC) procedures across Europe.
  • Conducted a structured online questionnaire via European Heart Rhythm Association (EHRA) network and social media.
  • Included responses from 140 physicians across more than 20 countries.
  • Evaluated operator background, procedural setting, and antithrombotic regimens at discharge and follow-up.
  • 67.4% of respondents were electrophysiologists, mainly from university hospitals (44.9%).
  • Most centers reported an annual procedural volume of 1–20 LAAC procedures, predominantly for major bleeding (64.0%).
  • Dual antiplatelet therapy (DAPT) was most common for bleeding indications, while direct oral anticoagulation (DOAC) was preferred for stroke prevention (41.1%).

Structured PICO

P
Population
140 physicians from more than 20 countries (mostly electrophysiologists, 67.4%) participating in an EHRA survey on LAAC practice patterns.
I
Intervention
Online questionnaire on operator background, procedural setting, and antithrombotic regimens at discharge and follow-up for left atrial appendage closure (LAAC).
O
Outcome
Current practice patterns regarding LAAC procedures and post-procedural antithrombotic strategies.

There is substantial diversity in post-LAAC antithrombotic management across European centers, highlighting the need for standardized guidelines.

Cite This Study

Urbanek et al. (2026) studied this question.

synapsesocial.com/papers/6a3f97e8125782b61d865a88https://doi.org/10.1093/europace/euag105.388
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Percutaneous Left Atrial Appendage Closure: Current Evidence and Procedural Insights2025 · 1 citations
  2. 2Clinical Outcomes of Different Stroke Prevention Strategies in Patients With Inadvertent Left Atrial Appendage Electrical Isolation2026
  3. 3Short-Term Anticoagulation versus Dual Antiplatelet Therapy for Preventing Device Thrombosis Following Left Atrial Appendage Closure: The ANDES Randomized Clinical Trial2025 · 22 citations
  4. 4Recent Trials of Left Atrial Appendage Closure versus Oral Anticoagulants: An Optimistic View2026
  5. 5Left Atrial Appendage Closure vs. Oral Anticoagulation in Patients With Atrial Fibrillation: An Updated Systematic Review and Meta‐Analysis of Randomized Controlled Trials2026 · 1 citations